Optimal balloon positioning for the proximal optimization technique? An experimental bench study.

ABSTRACT

AIMS: The proximal optimization technique (POT) in coronary bifurcation stenting improves apposition and side-branch obstruction. The POT balloon should be positioned with the distal radio-opaque marker at the carina cut plane. However, the real impact of positioning remains unknown. METHODS AND RESULTS: Synergy™ stents (Boston Scientific, USA) were implanted on left-main fractal bench models. Initial POT was performed in 3 positions according to distal shoulder position (loss of balloon parallelism) relative to the carina cut plane (n = 5/group) i) "proximal", 1 mm before carina; ii) "medium", just at carina; iii) "distal", 1 mm after carina. Results were quantified on 2D- and 3D-OCT. Compared to implantation, initial POT improved malapposition in all positions ("proximal" 61.5 ±â€¯1.4% vs. 5.1 ±â€¯2.7%; "medium" 60.2 ±â€¯2.4% vs. 1.3 ±â€¯0.6%; "distal" 60.5 ±â€¯2.9% vs. 1.1 ±â€¯1.8%, p < 0.05). However, residual malapposition was greater in "proximal" position (p < 0.05). "Proximal", unlike "medium" or "distal" POT, also failed to improve side-branch obstruction. Conversely, "distal" POT significantly overstretched the main-branch ostium, with stent/artery ratio 1.22 ±â€¯0.04 vs. 1.11 ±â€¯0.07 for "medium" POT (p < 0.05). CONCLUSION: Shoulder positioning is essential to optimize the mechanical benefit of POT without main-branch overstretch (too distal position). Experimentally, the best position is just at the carina cut plane ("medium").