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A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
Akoume, Marie-Yvonne; Elbakry, Mohamed; Veillette, Maxime; Franco, Anita; Nada, Dina; Labelle, Hubert; Mac-Thiong, Jean-Marc; Grimard, Guy; Ouellet, Jean; Parent, Stefan; Rivard, Charles-Hilaire; Lombardi, Giovanni; Colombini, Alessandra; Banfi, Giuseppe; Brayda-Bruno, Marco; Gorman, Kristen F; Moreau, Alain.
Affiliation
  • Akoume MY; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Elbakry M; Department of Pharmacology and Toxicology, Faculty of Medicine, Université des Sciences de la Santé (USS) de Libreville, Libreville, Gabon.
  • Veillette M; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Franco A; Biochemistry section, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt.
  • Nada D; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Labelle H; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Mac-Thiong JM; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Grimard G; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Ouellet J; LIS3D Laboratory, Sainte-Justine University Hospital Research Center, Montréal, Quebec, Canada.
  • Parent S; Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Rivard CH; Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Lombardi G; Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Colombini A; Orthopedic Division, The Montreal Children's Hospital, Department of Surgery, McGill University, Montréal, Quebec, Canada.
  • Banfi G; Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Brayda-Bruno M; Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
  • Gorman KF; IRCCS Istituto Ortopedico Galeazzi, Milano, Italy.
  • Moreau A; Department of Physiology and Pharmacology, Gdansk University of Physical Education & Sport, Gdansk, Poland.
Sci Rep ; 9(1): 10074, 2019 07 11.
Article in En | MEDLINE | ID: mdl-31296888
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Scoliosis / GTP-Binding Protein alpha Subunits, Gi-Go / Receptors, Melatonin Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Child / Female / Humans / Male Language: En Journal: Sci Rep Year: 2019 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Scoliosis / GTP-Binding Protein alpha Subunits, Gi-Go / Receptors, Melatonin Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Child / Female / Humans / Male Language: En Journal: Sci Rep Year: 2019 Document type: Article