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Mg2+ restriction downregulates NCC through NEDD4-2 and prevents its activation by hypokalemia.
Ferdaus, Mohammed Z; Mukherjee, Anindit; Nelson, Jonathan W; Blatt, Philip J; Miller, Lauren N; Terker, Andrew S; Staub, Olivier; Lin, Dao-Hong; McCormick, James A.
Affiliation
  • Ferdaus MZ; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
  • Mukherjee A; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
  • Nelson JW; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
  • Blatt PJ; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
  • Miller LN; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
  • Terker AS; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Staub O; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.
  • Lin DH; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • McCormick JA; Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon.
Am J Physiol Renal Physiol ; 317(4): F825-F838, 2019 10 01.
Article in En | MEDLINE | ID: mdl-31364380
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nedd4 Ubiquitin Protein Ligases / Hypokalemia / Magnesium Deficiency Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Year: 2019 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nedd4 Ubiquitin Protein Ligases / Hypokalemia / Magnesium Deficiency Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Year: 2019 Document type: Article