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A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology.
Birket, Matthew J; Raibaud, Sophie; Lettieri, Miriam; Adamson, Antony D; Letang, Valerie; Cervello, Pauline; Redon, Nicolas; Ret, Gwenaelle; Viale, Sandra; Wang, Bing; Biton, Bruno; Guillemot, Jean-Claude; Mikol, Vincent; Leonard, John P; Hanley, Neil A; Orsini, Cecile; Itier, Jean-Michel.
Affiliation
  • Birket MJ; Sanofi, Translational Sciences Unit, Sanofi, 13 quai Jules Guesdes, 94400 Vitry-sur-Seine, France; Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK. Electronic address: matthew.birket@manchester.ac.
  • Raibaud S; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Lettieri M; Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
  • Adamson AD; Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
  • Letang V; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Cervello P; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Redon N; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Ret G; Sanofi, Translational Sciences Unit, Sanofi, 13 quai Jules Guesdes, 94400 Vitry-sur-Seine, France.
  • Viale S; Sanofi, Translational Sciences Unit, Sanofi, 13 quai Jules Guesdes, 94400 Vitry-sur-Seine, France.
  • Wang B; Sanofi, GBD-Analytical R&D, 211 Second Avenue, Waltham, MA 02451, USA.
  • Biton B; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Guillemot JC; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Mikol V; Sanofi, Translational Sciences Unit, Avenue Pierre Brossolette, 91380 Chilly-Mazarin, France.
  • Leonard JP; Sanofi, Rare Disease Science Unit, 153 Second Avenue, Waltham, MA 02451, USA.
  • Hanley NA; Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK; Endocrinology Department, Manchester University NHS Foundation Trust, Grafton Street, Manchester M13 9WU, UK.
  • Orsini C; Sanofi, Translational Sciences Unit, Sanofi, 13 quai Jules Guesdes, 94400 Vitry-sur-Seine, France.
  • Itier JM; Sanofi, Translational Sciences Unit, Sanofi, 13 quai Jules Guesdes, 94400 Vitry-sur-Seine, France. Electronic address: jean-michel.itier@sanofi.com.
Stem Cell Reports ; 13(2): 380-393, 2019 08 13.
Article in En | MEDLINE | ID: mdl-31378672
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Fabry Disease / Myocytes, Cardiac / Lysosomal Membrane Proteins / Receptors, Scavenger / Models, Biological Limits: Humans Language: En Journal: Stem Cell Reports Year: 2019 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Fabry Disease / Myocytes, Cardiac / Lysosomal Membrane Proteins / Receptors, Scavenger / Models, Biological Limits: Humans Language: En Journal: Stem Cell Reports Year: 2019 Document type: Article