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Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice.
Keane, P C; Hanson, P S; Patterson, L; Blain, P G; Hepplewhite, P; Khundakar, A A; Judge, S J; Kahle, P J; LeBeau, F E N; Morris, C M.
Affiliation
  • Keane PC; Medical Toxicology Centre, Wolfson Building, Newcastle University, Claremont Place, Newcastle-Upon Tyne, NE2 4AA, UK; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
  • Hanson PS; Medical Toxicology Centre, Wolfson Building, Newcastle University, Claremont Place, Newcastle-Upon Tyne, NE2 4AA, UK.
  • Patterson L; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK; Alzheimer's Society Doctoral Training Centre, Newcastle University, Edwardson Building, Newcastle upon Tyne, NE4 5PL, UK.
  • Blain PG; Medical Toxicology Centre, Wolfson Building, Newcastle University, Claremont Place, Newcastle-Upon Tyne, NE2 4AA, UK.
  • Hepplewhite P; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
  • Khundakar AA; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
  • Judge SJ; Medical Toxicology Centre, Wolfson Building, Newcastle University, Claremont Place, Newcastle-Upon Tyne, NE2 4AA, UK; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
  • Kahle PJ; German Center for Neurodegenerative Diseases (DZNE) Tübingen, Hertie Institute for Clinical Brain Research, Laboratory of Functional Neurogenetics, University of TÜbingen, 72076 Tübingen, Germany.
  • LeBeau FEN; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
  • Morris CM; Medical Toxicology Centre, Wolfson Building, Newcastle University, Claremont Place, Newcastle-Upon Tyne, NE2 4AA, UK; Institute for Neuroscience, Newcastle University, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK; Alzheimer's Society Doctoral Training Centre, Newcastle Unive
Neurosci Lett ; 711: 134437, 2019 10 15.
Article in En | MEDLINE | ID: mdl-31422098

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trichloroethylene / Parkinsonian Disorders / Dopaminergic Neurons / Nerve Degeneration / Neurotoxins Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Neurosci Lett Year: 2019 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trichloroethylene / Parkinsonian Disorders / Dopaminergic Neurons / Nerve Degeneration / Neurotoxins Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Neurosci Lett Year: 2019 Document type: Article