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Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.
Keulen, Danielle van; Pouwer, Marianne G; Emilsson, Valur; Matic, Ljubica Perisic; Pieterman, Elsbet J; Hedin, Ulf; Gudnason, Vilmundur; Jennings, Lori L; Holmstrøm, Kim; Nielsen, Boye Schnack; Pasterkamp, Gerard; Lindeman, Jan H N; van Gool, Alain J; Sollewijn Gelpke, Maarten D; Princen, Hans M G; Tempel, Dennie.
Affiliation
  • Keulen DV; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Pouwer MG; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Emilsson V; Quorics B.V., Rotterdam, The Netherlands.
  • Matic LP; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
  • Pieterman EJ; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
  • Hedin U; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.
  • Jennings LL; Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland.
  • Holmstrøm K; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
  • Nielsen BS; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
  • Pasterkamp G; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
  • Lindeman JHN; Icelandic Heart Association, Kopavogur, Iceland.
  • van Gool AJ; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Sollewijn Gelpke MD; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States.
  • Princen HMG; Bioneer A/S, Hørsholm, Denmark.
  • Tempel D; Bioneer A/S, Hørsholm, Denmark.
PLoS One ; 14(8): e0221477, 2019.
Article in En | MEDLINE | ID: mdl-31461490
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Apolipoproteins E / Atherosclerosis / Cholesterol Ester Transfer Proteins / Oncostatin M Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: PLoS One Year: 2019 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Apolipoproteins E / Atherosclerosis / Cholesterol Ester Transfer Proteins / Oncostatin M Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: PLoS One Year: 2019 Document type: Article