Fertility preservation with successful pregnancy outcome in a patient with transplanted heart and non-Hodgkin's lymphoma - a case report.
BMC Pregnancy Childbirth
; 19(1): 421, 2019 Nov 19.
Article
in En
| MEDLINE
| ID: mdl-31744460
ABSTRACT
BACKGROUND:
Fertility preservation must be discussed with reproductive age women before cancer treatment. Heart transplantation raises complex issues in pregnancy. Pregnancy in a heart transplant woman after pelvic irradiation involves close multidisciplinary follow-up to avoid complications in the mother and the foetus. We report the first live birth in a heart transplant woman after pelvic irradiation, chemotherapy and fertility preservation. CASE PRESENTATION A 36-year-old heart transplant woman with pelvic non-Hodgkin lymphoma spared her fertility, with cryopreservation of oocytes and embryos, before chemotherapy and pelvic irradiation. After multidisciplinary discussion and pre-conception evaluation, pregnancy was achieved. A close follow-up by a multidisciplinary team allowed a normal pregnancy without maternal or foetal complications and the delivery of a healthy infant.CONCLUSIONS:
Achieving pregnancy in heart transplant women with iatrogenic ovarian failure after oncologic treatment including pelvic irradiation is possible and can be successful. Careful and close surveillance by a multidisciplinary team is mandatory due to increased risk of maternal and foetal complications.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications, Neoplastic
/
Lymphoma, Non-Hodgkin
/
Cryopreservation
/
Heart Transplantation
/
Fertility Preservation
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
BMC Pregnancy Childbirth
Year:
2019
Document type:
Article