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Pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency in zebrafish results in fatal seizures and metabolic aberrations.
Ciapaite, Jolita; Albersen, Monique; Savelberg, Sanne M C; Bosma, Marjolein; Tessadori, Federico; Gerrits, Johan; Lansu, Nico; Zwakenberg, Susan; Bakkers, Jeroen P W; Zwartkruis, Fried J T; van Haaften, Gijs; Jans, Judith J; Verhoeven-Duif, Nanda M.
Affiliation
  • Ciapaite J; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands. Electronic address: j.ciapaite@umcutrecht.nl.
  • Albersen M; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Savelberg SMC; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Bosma M; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Tessadori F; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Hubrecht Institute-KNAW and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands.
  • Gerrits J; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Lansu N; Hubrecht Institute-KNAW and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands.
  • Zwakenberg S; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Department of Molecular Cancer Research, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Bakkers JPW; Hubrecht Institute-KNAW and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands; Department of Medical Physiology, University Medical Center Utrecht, 3584 CM Utrecht, the Netherlands.
  • Zwartkruis FJT; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Department of Molecular Cancer Research, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • van Haaften G; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Jans JJ; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
  • Verhoeven-Duif NM; Department of Genetics, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands; Center for Molecular Medicine, University Medical Center Utrecht, 3584 EA Utrecht, the Netherlands.
Biochim Biophys Acta Mol Basis Dis ; 1866(3): 165607, 2020 03 01.
Article in En | MEDLINE | ID: mdl-31759955
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridoxaminephosphate Oxidase / Seizures / Zebrafish / Brain Diseases, Metabolic / Hypoxia-Ischemia, Brain / Metabolic Diseases Type of study: Etiology_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Mol Basis Dis Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridoxaminephosphate Oxidase / Seizures / Zebrafish / Brain Diseases, Metabolic / Hypoxia-Ischemia, Brain / Metabolic Diseases Type of study: Etiology_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Mol Basis Dis Year: 2020 Document type: Article