A phase II of gemcitabine combined with pazopanib followed by pazopanib maintenance, as second-line treatment in patients with advanced leiomyosarcomas: A unicancer French Sarcoma Group study (LMS03 study).

Pautier, P; Penel, N; Ray-Coquard, I; Italiano, A; Bompas, E; Delcambre, C; Bay, J-O; Bertucci, F; Delaye, J; Chevreau, C; Cupissol, D; Bozec, L; Eymard, J-C; Saada, E; Isambert, N; Guillemet, C; Rios, M; Piperno-Neumann, S; Chenuc, G; Duffaud, F

Pautier, P; Penel, N; Ray-Coquard, I; Italiano, A; Bompas, E; Delcambre, C; Bay, J-O; Bertucci, F; Delaye, J; Chevreau, C; Cupissol, D; Bozec, L; Eymard, J-C; Saada, E; Isambert, N; Guillemet, C; Rios, M; Piperno-Neumann, S; Chenuc, G; Duffaud, F.

Affiliation

Pautier P; Gustave Roussy, Villejuif, France. Electronic address: patricia.pautier@gustaveroussy.fr.
Penel N; Centre Oscar-Lambret & Lille University, Lille, France.
Ray-Coquard I; Centre Léon-Bérard & University Claude Bernard Lyon Est, Lyon, France.
Italiano A; Institut Bergonié, Bordeaux, France.
Bompas E; Institut de Cancérologie de L'Ouest, Angers-Nantes, France.
Delcambre C; Centre François-Baclesse, Caen, France.
Bay JO; Centre Jean-Perrin, Clermont-Ferrand, France.
Bertucci F; Institut Paoli-Calmettes, Marseille, France.
Delaye J; R&D Unicancer, Paris, France.
Chevreau C; Institut Claudius-Regaud, Toulouse, France.
Cupissol D; Institut Du Cancer, Montpellier, France.
Bozec L; Institut Curie, Hôpital René-Huguenin, Saint-Cloud, France.
Eymard JC; Institut Jean-Godinot, Reims, France.
Saada E; Centre Antoine-Lacassagne, Nice, France.
Isambert N; Centre Georges-François-Leclerc, Dijon, France.
Guillemet C; Centre Henri-Becquerel, Rouen, France.
Rios M; Centre Alexis-Vautrin, Vandoeuvre-les-Nancy, France.
Piperno-Neumann S; Institut Curie, Paris, France.
Chenuc G; Société Capionis, Paris, France.
Duffaud F; CHU La Timone, Marseille, France.

Eur J Cancer ; 125: 31-37, 2020 01.

Article in En | MEDLINE | ID: mdl-31835236

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Deoxycytidine/analogs & derivatives; Leiomyosarcoma/drug therapy; Pyrimidines/therapeutic use; Sulfonamides/therapeutic use; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Deoxycytidine/pharmacology; Deoxycytidine/therapeutic use; Female; Humans; Indazoles; Male; Middle Aged; Pyrimidines/pharmacology; Sulfonamides/pharmacology; Gemcitabine

Key words

Chemotherapy; Leiomyosarcoma; Maintenance therapy; Metastatic disease; Pazopanib

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Antineoplastic Combined Chemotherapy Protocols / Deoxycytidine / Leiomyosarcoma Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur J Cancer Year: 2020 Document type: Article

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