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Successful treatment of a PNH patient non-responsive to eculizumab with the novel complement C5 inhibitor coversin (nomacopan).
Schols, Saskia; Nunn, Miles A; Mackie, Ian; Weston-Davies, Wynne; Nishimura, Jun-Ichi; Kanakura, Yuzuru; Blijlevens, Nicole; Muus, Petra; Langemeijer, Saskia.
Affiliation
  • Schols S; Department of Hematology, Radboudumc, Nijmegen, The Netherlands.
  • Nunn MA; Akari Therapeutics, London, UK.
  • Mackie I; Haemostasis Research unit, Department of Haematology, University College London, London, UK.
  • Weston-Davies W; Akari Therapeutics, London, UK.
  • Nishimura JI; Department of Haematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Kanakura Y; Department of Haematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Blijlevens N; Department of Hematology, Radboudumc, Nijmegen, The Netherlands.
  • Muus P; Department of Hematology, Radboudumc, Nijmegen, The Netherlands.
  • Langemeijer S; Department of Haematology, King's College Hospital, London, UK.
Br J Haematol ; 188(2): 334-337, 2020 01.
Article in En | MEDLINE | ID: mdl-31840801
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Complement C5 / Complement Inactivating Agents / Antibodies, Monoclonal, Humanized / Hemoglobinuria, Paroxysmal Limits: Adult / Animals / Humans / Male Language: En Journal: Br J Haematol Year: 2020 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Complement C5 / Complement Inactivating Agents / Antibodies, Monoclonal, Humanized / Hemoglobinuria, Paroxysmal Limits: Adult / Animals / Humans / Male Language: En Journal: Br J Haematol Year: 2020 Document type: Article