Homogenous Scavenging Resolves Low-Purification Yield/Selectivity Caused by Secondary Binding of Protein-A to Antigen-Binding Antibody Fragments.

Anees, Palapuravan; Gauthier, Marc A

Anees, Palapuravan; Gauthier, Marc A.

Affiliation

Anees P; Institut National de la Recherche Scientifique (INRS), EMT Research Center , 1650 boul. Lionel-Boulet , Varennes , J3X 1S2 , Canada.
Gauthier MA; Institut National de la Recherche Scientifique (INRS), EMT Research Center , 1650 boul. Lionel-Boulet , Varennes , J3X 1S2 , Canada.

Biomacromolecules ; 21(2): 825-829, 2020 02 10.

Article in En | MEDLINE | ID: mdl-31841628

Subject(s)

Antigen-Antibody Complex/metabolism; Chromatography, Affinity/methods; Immunoglobulin Fab Fragments/metabolism; Immunoglobulin Fc Fragments/metabolism; Staphylococcal Protein A/metabolism; Animals; Antigen-Antibody Complex/isolation & purification; Humans; Immunoglobulin Fab Fragments/isolation & purification; Immunoglobulin Fc Fragments/isolation & purification; Protein Binding/physiology; Staphylococcal Protein A/isolation & purification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Protein A / Immunoglobulin Fab Fragments / Immunoglobulin Fc Fragments / Chromatography, Affinity / Antigen-Antibody Complex Limits: Animals / Humans Language: En Journal: Biomacromolecules Year: 2020 Document type: Article

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