Chronic Microangiopathy Due to DCR-MYC, a Myc-Targeted Short Interfering RNA.

Miller, Aaron J; Chang, Anthony; Cunningham, Patrick N

Miller, Aaron J; Chang, Anthony; Cunningham, Patrick N.

Affiliation

Miller AJ; Department of Pathology, University of Chicago, Chicago, IL.
Chang A; Department of Pathology, University of Chicago, Chicago, IL.
Cunningham PN; Department of Medicine, University of Chicago, Chicago, IL. Electronic address: pcunningham@medicine.bsd.uchicago.edu.

Am J Kidney Dis ; 75(4): 513-516, 2020 04.

Article in En | MEDLINE | ID: mdl-31866228

Subject(s)

Proto-Oncogene Proteins c-myc/genetics; RNA, Small Interfering/adverse effects; RNA, Small Interfering/genetics; Thrombotic Microangiopathies/chemically induced; Thrombotic Microangiopathies/genetics; Aged; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/adverse effects; Chronic Disease; Drug Delivery Systems/adverse effects; Drug Delivery Systems/methods; Fatal Outcome; Female; Gene Targeting/adverse effects; Gene Targeting/methods; Humans; Proto-Oncogene Proteins c-myc/antagonists & inhibitors; RNA, Small Interfering/administration & dosage; Thrombotic Microangiopathies/diagnosis

Key words

Thrombotic microangiopathy (TMA); adverse drug event; anti-cancer agent; case report; chemotherapy; experimental treatment; investigational drug; kidney biopsy; onconephrology; oncotherapy; renal function; short interfering RNA (siRNA)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-myc / RNA, Small Interfering / Thrombotic Microangiopathies Type of study: Diagnostic_studies Limits: Aged / Female / Humans Language: En Journal: Am J Kidney Dis Year: 2020 Document type: Article

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