Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients.

Dickson, Robert P; Schultz, Marcus J; van der Poll, Tom; Schouten, Laura R; Falkowski, Nicole R; Luth, Jenna E; Sjoding, Michael W; Brown, Christopher A; Chanderraj, Rishi; Huffnagle, Gary B; Bos, Lieuwe D J

Dickson, Robert P; Schultz, Marcus J; van der Poll, Tom; Schouten, Laura R; Falkowski, Nicole R; Luth, Jenna E; Sjoding, Michael W; Brown, Christopher A; Chanderraj, Rishi; Huffnagle, Gary B; Bos, Lieuwe D J.

Affiliation

Dickson RP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine.
Schultz MJ; Department of Microbiology and Immunology.
van der Poll T; Michigan Center for Integrative Research in Critical Care, Ann Arbor, Michigan.
Schouten LR; Intensive Care.
Falkowski NR; Infection and Immunity, University of Amsterdam, Amsterdam, the Netherlands; and.
Luth JE; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Sjoding MW; Centre for Experimental and Molecular Medicine and.
Brown CA; Intensive Care.
Chanderraj R; Infection and Immunity, University of Amsterdam, Amsterdam, the Netherlands; and.
Huffnagle GB; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine.
Bos LDJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine.

Am J Respir Crit Care Med ; 201(5): 555-563, 2020 03 01.

Article in En | MEDLINE | ID: mdl-31973575

Subject(s)

Lung/microbiology; Microbiota/genetics; Respiration, Artificial/statistics & numerical data; Respiratory Distress Syndrome/therapy; Adult; Aged; Bacterial Load; Bronchoalveolar Lavage Fluid/microbiology; Clostridiales; Cohort Studies; Critical Illness; Enterobacteriaceae; Female; Gastrointestinal Microbiome; Humans; Male; Middle Aged; Pasteurellaceae; Principal Component Analysis; Prognosis; Proportional Hazards Models; RNA, Ribosomal, 16S/genetics; Respiratory Distress Syndrome/microbiology

Key words

acute respiratory distress syndrome; lung injury; lung microbiome; prognosis

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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Respiration, Artificial / Respiratory Distress Syndrome / Microbiota / Lung Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am J Respir Crit Care Med Year: 2020 Document type: Article

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