Histopathological imaging database for oral cancer analysis.

ABSTRACT

The repository is composed of 1224 images divided into two sets of images with two different resolutions. First set consists of 89 histopathological images with the normal epithelium of the oral cavity and 439 images of Oral Squamous Cell Carcinoma (OSCC) in 100x magnification. The second set consists of 201 images with the normal epithelium of the oral cavity and 495 histopathological images of OSCC in 400x magnification. The images were captured using a Leica ICC50 HD microscope from Hematoxyline and Eosin (H&E) stained tissue slides collected, prepared and catalogued by medical experts from 230 patients. A subset of 269 images from the second data set was used to detect OSCC based on textural features [1]. Histopathology plays a very important role in diagnosing a disease. It is the investigation of biological tissues to detect the presence of diseased cells in microscopic detail. It usually involves a biopsy. Till date biopsy is the gold-standard test to diagnose cancer. The biopsy slides are examined based on various cytological criteria under a microscope. Therefore, there is a high possibility of not retaining uniformity and ensuring reproducibility in outcomes [2, 3]. Computational diagnostic tools, on the other hand, facilitate objective judgments by making the use of the quantitative measure. This dataset can be utilized in establishing automated diagnostic tool using Artificial Intelligence approaches.