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Biological evaluation of non-basic chalcone CYB-2 as a dual ABCG2/ABCB1 inhibitor.
Cai, Chao-Yun; Zhang, Wei; Wang, Jing-Quan; Lei, Zi-Ning; Zhang, Yun-Kai; Wang, Yi-Jun; Gupta, Pranav; Tan, Cai-Ping; Wang, Bo; Chen, Zhe-Sheng.
Affiliation
  • Cai CY; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, 135 Xingang West Road, Guangzhou 51027
  • Zhang W; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States; Institute of Plastic Surgery, Weifang Medical University, Weifang, Shandong 261041, PR China.
  • Wang JQ; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States.
  • Lei ZN; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States.
  • Zhang YK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States.
  • Wang YJ; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States.
  • Gupta P; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States.
  • Tan CP; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, 135 Xingang West Road, Guangzhou 510275, PR China. Electronic address: tancaip@mail.sysu.edu.cn.
  • Wang B; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, 135 Xingang West Road, Guangzhou 510275, PR China. Electronic address: ceswb@mail.sysu.edu.cn.
  • Chen ZS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, United States. Electronic address: chenz@stjohns.edu.
Biochem Pharmacol ; 175: 113848, 2020 05.
Article in En | MEDLINE | ID: mdl-32044354
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Multiple / Drug Resistance, Neoplasm / Chalcones / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Neoplasm Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Multiple / Drug Resistance, Neoplasm / Chalcones / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Neoplasm Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article