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IRF4 instructs effector Treg differentiation and immune suppression in human cancer.
Alvisi, Giorgia; Brummelman, Jolanda; Puccio, Simone; Mazza, Emilia Mc; Tomada, Elisa Paoluzzi; Losurdo, Agnese; Zanon, Veronica; Peano, Clelia; Colombo, Federico S; Scarpa, Alice; Alloisio, Marco; Vasanthakumar, Ajithkumar; Roychoudhuri, Rahul; Kallikourdis, Marinos; Pagani, Massimiliano; Lopci, Egesta; Novellis, Pierluigi; Blume, Jonas; Kallies, Axel; Veronesi, Giulia; Lugli, Enrico.
Affiliation
  • Alvisi G; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Brummelman J; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Puccio S; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Mazza EM; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Tomada EP; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Losurdo A; Humanitas Clinical and Research Center - IRCCS, Humanitas Cancer Center, Rozzano, Milan, Italy.
  • Zanon V; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Peano C; Division of Genetic and Biomedical Research, UOS Milan, National Research Council, Rozzano, Milan, Italy.
  • Colombo FS; Genomic Unit and.
  • Scarpa A; Humanitas Flow Cytometry Core, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Alloisio M; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
  • Vasanthakumar A; Division of Thoracic Surgery, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy.
  • Roychoudhuri R; Biomedical Science Department, Humanitas University, Rozzano, Milan, Italy.
  • Kallikourdis M; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
  • Pagani M; Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.
  • Lopci E; Adaptive Immunity Laboratory, Humanitas Clinical and Research Center, Rozzano, Milan.
  • Novellis P; Istituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi," Milan, Italy.
  • Blume J; Nuclear Medicine Department, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy.
  • Kallies A; Division of Thoracic Surgery, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy.
  • Veronesi G; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
  • Lugli E; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
J Clin Invest ; 130(6): 3137-3150, 2020 06 01.
Article in En | MEDLINE | ID: mdl-32125291
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / T-Lymphocytes, Regulatory / Interferon Regulatory Factors / Tumor Microenvironment / Neoplasm Proteins / Neoplasms Type of study: Prognostic_studies Limits: Aged / Aged80 / Animals / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / T-Lymphocytes, Regulatory / Interferon Regulatory Factors / Tumor Microenvironment / Neoplasm Proteins / Neoplasms Type of study: Prognostic_studies Limits: Aged / Aged80 / Animals / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2020 Document type: Article