Your browser doesn't support javascript.
loading
Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity.
Zhang, Xuan; Thummuri, Dinesh; Liu, Xingui; Hu, Wanyi; Zhang, Peiyi; Khan, Sajid; Yuan, Yaxia; Zhou, Daohong; Zheng, Guangrong.
Affiliation
  • Zhang X; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Thummuri D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Liu X; Department of Pharmacodynamics, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Hu W; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Zhang P; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Khan S; Department of Pharmacodynamics, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Yuan Y; Department of Pharmacodynamics, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States.
  • Zhou D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States. Electronic address: zhoudaohong@cop.ufl.edu.
  • Zheng G; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States. Electronic address: zhengg@cop.ufl.edu.
Eur J Med Chem ; 192: 112186, 2020 Apr 15.
Article in En | MEDLINE | ID: mdl-32145645
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Blood Platelets / Bcl-X Protein / Drug Discovery / Proteolysis / Aniline Compounds / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Blood Platelets / Bcl-X Protein / Drug Discovery / Proteolysis / Aniline Compounds / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article