Tumor microenvironment and NIR laser dual-responsive release of berberine 9-O-pyrazole alkyl derivative loaded in graphene oxide nanosheets for chemo-photothermal synergetic cancer therapy.

Du, Peifang; Yan, Jianhua; Long, Shuo; Xiong, Hongjie; Wen, Nachuan; Cai, Shundong; Wang, Yirong; Peng, Dongming; Liu, Zhenbao; Liu, Yanfei

Du, Peifang; Yan, Jianhua; Long, Shuo; Xiong, Hongjie; Wen, Nachuan; Cai, Shundong; Wang, Yirong; Peng, Dongming; Liu, Zhenbao; Liu, Yanfei.

Affiliation

Du P; Department of Pharmaceutical Engineering, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan Province, P. R. China. liuyf@csu.edu.cn.

J Mater Chem B ; 8(18): 4046-4055, 2020 05 14.

Article in En | MEDLINE | ID: mdl-32248212

Subject(s)

Antineoplastic Agents/pharmacology; Berberine/pharmacology; Graphite/chemistry; Lasers; Nanoparticles/chemistry; Photothermal Therapy; Pyrazoles/pharmacology; A549 Cells; Animals; Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/chemistry; Apoptosis/drug effects; Berberine/analogs & derivatives; Berberine/chemistry; Cell Proliferation/drug effects; Cell Survival/drug effects; Cells, Cultured; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Particle Size; Pyrazoles/chemistry; Surface Properties; Tumor Microenvironment/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Berberine / Nanoparticles / Photothermal Therapy / Graphite / Lasers / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: J Mater Chem B Year: 2020 Document type: Article

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