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Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1.
Cheng, Binbin; Ren, Yichang; Cao, Hao; Chen, Jianjun.
Affiliation
  • Cheng B; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Ren Y; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Cao H; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Chen J; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China. Electronic address: jchen21@smu.edu.cn.
Eur J Med Chem ; 199: 112377, 2020 Aug 01.
Article in En | MEDLINE | ID: mdl-32388281

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Resorcinols / Drug Discovery / B7-H1 Antigen / Proteolysis / Immune Checkpoint Inhibitors Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Resorcinols / Drug Discovery / B7-H1 Antigen / Proteolysis / Immune Checkpoint Inhibitors Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article