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Allosteric inhibitor of ß-catenin selectively targets oncogenic Wnt signaling in colon cancer.
Cheltsov, Anton; Nomura, Natsuko; Yenugonda, Venkata M; Roper, Jatin; Mukthavaram, Rajesh; Jiang, Pengfei; Her, Nam-Gu; Babic, Ivan; Kesari, Santosh; Nurmemmedov, Elmar.
Affiliation
  • Cheltsov A; Q-MOL LLC, San Diego, California, United States of America.
  • Nomura N; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Yenugonda VM; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Roper J; Division of Gastroenterology, Department of Medicine, Duke University, Durham, North Carolina, 27710, USA.
  • Mukthavaram R; Translational Neuro-Oncology Laboratories, Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Jiang P; Translational Neuro-Oncology Laboratories, Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Her NG; Korea Institute of Radiological and Medical Sciences, 75 Nowon-ro, Seoul, 01812, Korea.
  • Babic I; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Kesari S; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Nurmemmedov E; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USA. elmar.nurmammadov@providence.org.
Sci Rep ; 10(1): 8096, 2020 05 15.
Article in En | MEDLINE | ID: mdl-32415084
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Neoplastic Stem Cells / Beta Catenin / Small Molecule Libraries / Wnt Signaling Pathway / Neoplasms / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Sci Rep Year: 2020 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Neoplastic Stem Cells / Beta Catenin / Small Molecule Libraries / Wnt Signaling Pathway / Neoplasms / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Sci Rep Year: 2020 Document type: Article