Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells.

Her, Nam-Gu; Kesari, Santosh; Nurmemmedov, Elmar

Her, Nam-Gu; Kesari, Santosh; Nurmemmedov, Elmar.

Affiliation

Her NG; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences , Seoul, Republic of Korea.
Kesari S; Department of Neuro-sciences and Neuro-therapeutics, John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center , Santa Monica, CA, USA.
Nurmemmedov E; Institute for Refractory Cancer Research, Current Address: Samsung Medical Center , Seoul, Republic of Korea.

Cell Cycle ; 19(13): 1590-1601, 2020 07.

Article in En | MEDLINE | ID: mdl-32423265

Subject(s)

Colonic Neoplasms/metabolism; Indoles/pharmacology; Pyrimidines/pharmacology; Thrombospondin 1/metabolism; Valosin Containing Protein/antagonists & inhibitors; Apoptosis/drug effects; Apoptosis/genetics; Cell Line, Tumor; Colonic Neoplasms/pathology; Drug Resistance, Neoplasm/drug effects; Drug Resistance, Neoplasm/genetics; Endoplasmic Reticulum Stress/drug effects; Endoplasmic Reticulum Stress/genetics; Gene Expression Regulation, Neoplastic/drug effects; Humans; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Thrombospondin 1/genetics; Up-Regulation/drug effects; Up-Regulation/genetics; Valosin Containing Protein/metabolism

Key words

Thrombospondin-1; cb-5083; p97; protein homeostasis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Colonic Neoplasms / Thrombospondin 1 / Valosin Containing Protein / Indoles Limits: Humans Language: En Journal: Cell Cycle Year: 2020 Document type: Article

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