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Refined construction of antibody-targeted nanoparticles leads to superior antigen binding and enhanced delivery of an entrapped payload to pancreatic cancer cells.
Greene, Michelle K; Nogueira, João C F; Tracey, Shannon R; Richards, Daniel A; McDaid, William J; Burrows, James F; Campbell, Katrina; Longley, Daniel B; Chudasama, Vijay; Scott, Christopher J.
Affiliation
  • Greene MK; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. c.scott@qub.ac.uk.
  • Nogueira JCF; Department of Chemistry, University College London, London, UK. v.chudasama@ucl.ac.uk.
  • Tracey SR; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. c.scott@qub.ac.uk.
  • Richards DA; Department of Chemistry, University College London, London, UK. v.chudasama@ucl.ac.uk.
  • McDaid WJ; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. c.scott@qub.ac.uk.
  • Burrows JF; School of Pharmacy, Queen's University Belfast, Belfast, UK.
  • Campbell K; Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, UK.
  • Longley DB; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. c.scott@qub.ac.uk.
  • Chudasama V; Department of Chemistry, University College London, London, UK. v.chudasama@ucl.ac.uk.
  • Scott CJ; The Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. c.scott@qub.ac.uk.
Nanoscale ; 12(21): 11647-11658, 2020 Jun 04.
Article in En | MEDLINE | ID: mdl-32436550
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Delivery Systems / Nanoparticles / Antibodies / Antigens, Neoplasm Limits: Humans Language: En Journal: Nanoscale Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Delivery Systems / Nanoparticles / Antibodies / Antigens, Neoplasm Limits: Humans Language: En Journal: Nanoscale Year: 2020 Document type: Article