3,4-Methylenedioxymethamphetamine causes retinal damage in C57BL/6J mice.

Ma, Y; Bian, C; Song, D; Yao, G; Nie, R

Ma, Y; Bian, C; Song, D; Yao, G; Nie, R.

Affiliation

Ma Y; Department of Ophthalmology, Tai'an City Central Hospital, Tai'an, People's Republic of China.
Bian C; Department of Ophthalmology, Tai'an City Central Hospital, Tai'an, People's Republic of China.
Song D; Department of Ophthalmology, The First People's Hospital of Tai'an, Tai'an, People's Republic of China.
Yao G; Department of Ophthalmology, Tai'an City Central Hospital, Tai'an, People's Republic of China.
Nie R; Department of Ophthalmology, The First People's Hospital of Tai'an, Tai'an, People's Republic of China.

Hum Exp Toxicol ; 39(11): 1556-1564, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32552070

Subject(s)

Hallucinogens/toxicity; N-Methyl-3,4-methylenedioxyamphetamine/toxicity; Retina/drug effects; Animals; Cytokines/metabolism; Electroretinography; Gene Expression Regulation/drug effects; Matrix Metalloproteinases/metabolism; Mice, Inbred C57BL; NF-kappa B/metabolism; Retina/metabolism; Retina/pathology; Retina/physiology; Retinal Diseases/chemically induced; Retinal Diseases/diagnosis; Retinal Diseases/metabolism; Retinal Diseases/pathology; Tight Junction Proteins/metabolism

Key words

3,4-Methylenedioxymethamphetamine; inflammatory responses; matrix metalloproteinase; retina; tight junction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / N-Methyl-3,4-methylenedioxyamphetamine / Hallucinogens Type of study: Diagnostic_studies / Etiology_studies Limits: Animals Language: En Journal: Hum Exp Toxicol Year: 2020 Document type: Article

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