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Synthetic interleukin 22 (IL-22) signaling reveals biological activity of homodimeric IL-10 receptor 2 and functional cross-talk with the IL-6 receptor gp130.
Mossner, Sofie; Kuchner, Marcus; Fazel Modares, Nastaran; Knebel, Birgit; Al-Hasani, Hadi; Floss, Doreen M; Scheller, Jürgen.
Affiliation
  • Mossner S; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Kuchner M; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Fazel Modares N; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Knebel B; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Al-Hasani H; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Floss DM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Scheller J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany jscheller@uni-duesseldorf.de.
J Biol Chem ; 295(35): 12378-12397, 2020 08 28.
Article in En | MEDLINE | ID: mdl-32611765
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukins / Cytokine Receptor gp130 / Interleukin-10 Receptor beta Subunit / Protein Multimerization Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukins / Cytokine Receptor gp130 / Interleukin-10 Receptor beta Subunit / Protein Multimerization Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Document type: Article