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Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.
McPhillie, Martin J; Zhou, Ying; Hickman, Mark R; Gordon, James A; Weber, Christopher R; Li, Qigui; Lee, Patty J; Amporndanai, Kangsa; Johnson, Rachel M; Darby, Heather; Woods, Stuart; Li, Zhu-Hong; Priestley, Richard S; Ristroph, Kurt D; Biering, Scott B; El Bissati, Kamal; Hwang, Seungmin; Hakim, Farida Esaa; Dovgin, Sarah M; Lykins, Joseph D; Roberts, Lucy; Hargrave, Kerrie; Cong, Hua; Sinai, Anthony P; Muench, Stephen P; Dubey, Jitender P; Prud'homme, Robert K; Lorenzi, Hernan A; Biagini, Giancarlo A; Moreno, Silvia N; Roberts, Craig W; Antonyuk, Svetlana V; Fishwick, Colin W G; McLeod, Rima.
Affiliation
  • McPhillie MJ; School of Chemistry, The University of Leeds, Leeds, United Kingdom.
  • Zhou Y; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
  • Hickman MR; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
  • Gordon JA; School of Chemistry, The University of Leeds, Leeds, United Kingdom.
  • Weber CR; Department of Pathology, The University of Chicago, Chicago, IL, United States.
  • Li Q; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
  • Lee PJ; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
  • Amporndanai K; Department of Biochemistry and Systems Biology, Faculty of Health and Life Sciences, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom.
  • Johnson RM; School of Biomedical Sciences, Faculty of Biological Sciences, and Astbury Centre for Structural Molecular Biology, The University of Leeds, Leeds, United Kingdom.
  • Darby H; School of Chemistry, The University of Leeds, Leeds, United Kingdom.
  • Woods S; Strathclyde Institute of Pharmacy and Biomedical Sciences, The University of Strathclyde, Glasgow, United Kingdom.
  • Li ZH; Department of Cellular Biology, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
  • Priestley RS; Department of Tropical Disease Biology, Research Center for Drugs and Diagnostics, The Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Ristroph KD; Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ, United States.
  • Biering SB; Department of Pathology, The University of Chicago, Chicago, IL, United States.
  • El Bissati K; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
  • Hwang S; Department of Pathology, The University of Chicago, Chicago, IL, United States.
  • Hakim FE; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
  • Dovgin SM; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
  • Lykins JD; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
  • Roberts L; Strathclyde Institute of Pharmacy and Biomedical Sciences, The University of Strathclyde, Glasgow, United Kingdom.
  • Hargrave K; Strathclyde Institute of Pharmacy and Biomedical Sciences, The University of Strathclyde, Glasgow, United Kingdom.
  • Cong H; School of Chemistry, The University of Leeds, Leeds, United Kingdom.
  • Sinai AP; Microbiology, Immunology and Molecular Genetics, The University of Kentucky College of Medicine, Lexington, KY, United States.
  • Muench SP; School of Biomedical Sciences, Faculty of Biological Sciences, and Astbury Centre for Structural Molecular Biology, The University of Leeds, Leeds, United Kingdom.
  • Dubey JP; Animal Parasitic Diseases Laboratory (APDL), USDA-ARS, Beltsville, MD, United States.
  • Prud'homme RK; Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ, United States.
  • Lorenzi HA; Department of Infectious Diseases, J Craig Venter Institute, Rockville, MD, United States.
  • Biagini GA; Department of Tropical Disease Biology, Research Center for Drugs and Diagnostics, The Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Moreno SN; Department of Cellular Biology, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
  • Roberts CW; Strathclyde Institute of Pharmacy and Biomedical Sciences, The University of Strathclyde, Glasgow, United Kingdom.
  • Antonyuk SV; Department of Biochemistry and Systems Biology, Faculty of Health and Life Sciences, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom.
  • Fishwick CWG; School of Chemistry, The University of Leeds, Leeds, United Kingdom.
  • McLeod R; Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL, United States.
Front Cell Infect Microbiol ; 10: 203, 2020.
Article in En | MEDLINE | ID: mdl-32626661
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 / 3_ND Database: MEDLINE Main subject: Parasites / Toxoplasma / Toxoplasmosis Limits: Animals Language: En Journal: Front Cell Infect Microbiol Year: 2020 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 / 3_ND Database: MEDLINE Main subject: Parasites / Toxoplasma / Toxoplasmosis Limits: Animals Language: En Journal: Front Cell Infect Microbiol Year: 2020 Document type: Article