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Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections.
Kirsch, Philine; Stein, Saskia C; Berwanger, Aylin; Rinkes, Julia; Jakob, Valentin; Schulz, Thomas F; Empting, Martin.
Affiliation
  • Kirsch P; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus E8.1, 66123, Saarbrücken, Germany; German
  • Stein SC; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 66123, Saarbrücken, Germany; Institute of Virology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
  • Berwanger A; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus E8.1, 66123, Saarbrücken, Germany; German
  • Rinkes J; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus E8.1, 66123, Saarbrücken, Germany; German
  • Jakob V; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus E8.1, 66123, Saarbrücken, Germany; German
  • Schulz TF; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 66123, Saarbrücken, Germany; Institute of Virology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
  • Empting M; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus E8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus E8.1, 66123, Saarbrücken, Germany; German
Eur J Med Chem ; 202: 112525, 2020 Sep 15.
Article in En | MEDLINE | ID: mdl-32634628
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Triazoles / Nuclear Proteins / Herpesviridae Infections / Herpesvirus 8, Human / Isoquinolines Type of study: Risk_factors_studies Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Triazoles / Nuclear Proteins / Herpesviridae Infections / Herpesvirus 8, Human / Isoquinolines Type of study: Risk_factors_studies Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article