Diselenide-Mediated Catalytic Functionalization of Hydrophosphoryl Compounds.
Org Lett
; 22(15): 5811-5816, 2020 08 07.
Article
in En
| MEDLINE
| ID: mdl-32672974
ABSTRACT
We report a diaryldiselenide catalyst for cross-dehydrogenative nucleophilic functionalization of hydrophosphoryl compounds. The proposed organocatalytic cycle closely resembles the mechanism of the Atherton-Todd reaction, with the catalyst serving as a recyclable analogue of the halogenating agent employed in the named reaction. Phosphorus and selenium NMR studies reveal the existence of a P-Se bond intermediate, and structural analyses indicate a stereospecific reaction.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Lett
Year:
2020
Document type:
Article