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UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer.
Liu, Yajing; Awadia, Sahezeel; Delaney, Amy; Sitto, Merna; Engelke, Carl G; Patel, Heli; Calcaterra, Andrew; Zelenka-Wang, Sylvia; Lee, Hojin; Contessa, Joseph; Neamati, Nouri; Ljungman, Mats; Lawrence, Theodore S; Morgan, Meredith A; Rehemtulla, Alnawaz.
Affiliation
  • Liu Y; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Awadia S; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Delaney A; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Sitto M; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Engelke CG; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Patel H; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Calcaterra A; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Zelenka-Wang S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Lee H; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Contessa J; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Neamati N; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
  • Ljungman M; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Lawrence TS; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Morgan MA; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA.
  • Rehemtulla A; Department of Radiation Oncology, University of Michigan Medical School and Rogel Cancer Center, Ann Arbor, MI, USA. Electronic address: alnawaz@med.umich.edu.
Transl Oncol ; 13(11): 100834, 2020 Nov.
Article in En | MEDLINE | ID: mdl-32688248
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Language: En Journal: Transl Oncol Year: 2020 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Language: En Journal: Transl Oncol Year: 2020 Document type: Article