Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis.

Svendsen, Pia; Etzerodt, Anders; Deleuran, Bent W; Moestrup, Søren K

Svendsen, Pia; Etzerodt, Anders; Deleuran, Bent W; Moestrup, Søren K.

Affiliation

Svendsen P; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Etzerodt A; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
Deleuran BW; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Moestrup SK; Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Sci Rep ; 10(1): 12447, 2020 07 24.

Article in En | MEDLINE | ID: mdl-32710083

Subject(s)

Arthritis, Experimental/immunology; Arthritis, Rheumatoid/immunology; Receptors, Cell Surface/deficiency; Animals; Antigens, CD/genetics; Antigens, CD/immunology; Antigens, Differentiation, Myelomonocytic/genetics; Antigens, Differentiation, Myelomonocytic/immunology; Arthritis, Experimental/blood; Arthritis, Experimental/diagnosis; Arthritis, Experimental/pathology; Arthritis, Rheumatoid/blood; Arthritis, Rheumatoid/diagnosis; Arthritis, Rheumatoid/pathology; Collagen Type II/immunology; Cytokines/blood; Cytokines/immunology; Cytokines/metabolism; Disease Progression; Humans; Joints/immunology; Joints/pathology; Macrophages/immunology; Macrophages/metabolism; Male; Mice; Mice, Knockout; Receptors, Cell Surface/genetics; Receptors, Cell Surface/immunology; Severity of Illness Index; Synovial Fluid/immunology; Th1 Cells/immunology; Th1 Cells/metabolism; Th1-Th2 Balance; Th2 Cells/immunology; Th2 Cells/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Arthritis, Rheumatoid / Receptors, Cell Surface Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Sci Rep Year: 2020 Document type: Article

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