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Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study.
Saddiki, Hana; Fayosse, Aurore; Cognat, Emmanuel; Sabia, Séverine; Engelborghs, Sebastiaan; Wallon, David; Alexopoulos, Panagiotis; Blennow, Kaj; Zetterberg, Henrik; Parnetti, Lucilla; Zerr, Inga; Hermann, Peter; Gabelle, Audrey; Boada, Mercè; Orellana, Adelina; de Rojas, Itziar; Lilamand, Matthieu; Bjerke, Maria; Van Broeckhoven, Christine; Farotti, Lucia; Salvadori, Nicola; Diehl-Schmid, Janine; Grimmer, Timo; Hourregue, Claire; Dugravot, Aline; Nicolas, Gaël; Laplanche, Jean-Louis; Lehmann, Sylvain; Bouaziz-Amar, Elodie; Hugon, Jacques; Tzourio, Christophe; Singh-Manoux, Archana; Paquet, Claire; Dumurgier, Julien.
Affiliation
  • Saddiki H; Université de Paris, Inserm U1153, Epidemiology of Ageing and Neurodegenerative diseases, Paris, France.
  • Fayosse A; Université de Paris, Inserm U1153, Epidemiology of Ageing and Neurodegenerative diseases, Paris, France.
  • Cognat E; Cognitive Neurology Center, Lariboisiere-Fernand Widal Hospital, AP-HP, Université de Paris, Paris, France.
  • Sabia S; Université de Paris, Inserm U1153, Epidemiology of Ageing and Neurodegenerative diseases, Paris, France.
  • Engelborghs S; Department of Neurology, Universitair Ziekenhuis Brussel, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium.
  • Wallon D; Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Alexopoulos P; Inserm U1245, Rouen University Hospital, Department of Neurology and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.
  • Blennow K; Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Faculty of Medicine, Technical University of Munich, Munich, Germany.
  • Zetterberg H; Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden.
  • Parnetti L; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Zerr I; Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden.
  • Hermann P; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Gabelle A; Department of Neurodegenerative Disease, Institute of Neurology, University College London, UK Dementia Research Institute, London, United Kingdom.
  • Boada M; Center for Memory Disturbances-Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Italy.
  • Orellana A; Department of Neurology, Clinical Dementia Center, University Medical Center Göttingen and German Center for Neurodegenerative Diseases, Göttingen, Germany.
  • de Rojas I; Department of Neurology, Clinical Dementia Center, University Medical Center Göttingen and German Center for Neurodegenerative Diseases, Göttingen, Germany.
  • Lilamand M; Department of Neurology, Memory Research and Resources Centre, University of Montpellier, Montpellier, France.
  • Bjerke M; Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurciències Aplicades, Universitat International de Catalunya, Barcelona, Spain.
  • Van Broeckhoven C; Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurciències Aplicades, Universitat International de Catalunya, Barcelona, Spain.
  • Farotti L; Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurciències Aplicades, Universitat International de Catalunya, Barcelona, Spain.
  • Salvadori N; Cognitive Neurology Center, Lariboisiere-Fernand Widal Hospital, AP-HP, Université de Paris, Paris, France.
  • Diehl-Schmid J; VIB Center for Molecular Neurology, Institute Born-Bunge and Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Grimmer T; VIB Center for Molecular Neurology, Institute Born-Bunge and Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Hourregue C; Center for Memory Disturbances-Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Italy.
  • Dugravot A; Center for Memory Disturbances-Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Italy.
  • Nicolas G; Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Faculty of Medicine, Technical University of Munich, Munich, Germany.
  • Laplanche JL; Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Faculty of Medicine, Technical University of Munich, Munich, Germany.
  • Lehmann S; Cognitive Neurology Center, Lariboisiere-Fernand Widal Hospital, AP-HP, Université de Paris, Paris, France.
  • Bouaziz-Amar E; Université de Paris, Inserm U1153, Epidemiology of Ageing and Neurodegenerative diseases, Paris, France.
  • Hugon J; Department of Biochemistry and Molecular Biology, Lariboisière Hospital, APHP, Paris, France.
  • Tzourio C; Department of Biochemistry, University of Montpellier, Montpellier, France.
  • Singh-Manoux A; Department of Biochemistry and Molecular Biology, Lariboisière Hospital, APHP, Paris, France.
  • Dumurgier J; Cognitive Neurology Center, Lariboisiere-Fernand Widal Hospital, AP-HP, Université de Paris, Paris, France.
PLoS Med ; 17(8): e1003289, 2020 08.
Article in En | MEDLINE | ID: mdl-32817639
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Aging / Apolipoprotein E4 / Alzheimer Disease Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Aging / Apolipoprotein E4 / Alzheimer Disease Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Year: 2020 Document type: Article