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Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation.
Olonisakin, Tolani F; Suber, Tomeka; Gonzalez-Ferrer, Shekina; Xiong, Zeyu; Peñaloza, Hernán F; van der Geest, Rick; Xiong, Yuting; Osei-Hwedieh, David O; Tejero, Jesús; Rosengart, Matthew R; Mars, Wendy M; Van Tyne, Daria; Perlegas, Andreas; Brashears, Samuel; Kim-Shapiro, Daniel B; Gladwin, Mark T; Bachman, Michael A; Hod, Eldad A; St Croix, Claudette; Tyurina, Yulia Y; Kagan, Valerian E; Mallampalli, Rama K; Ray, Anuradha; Ray, Prabir; Lee, Janet S.
Affiliation
  • Olonisakin TF; Medical Scientist Training Program.
  • Suber T; Acute Lung Injury Center of Excellence.
  • Gonzalez-Ferrer S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Xiong Z; Acute Lung Injury Center of Excellence.
  • Peñaloza HF; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • van der Geest R; Acute Lung Injury Center of Excellence.
  • Xiong Y; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Osei-Hwedieh DO; Acute Lung Injury Center of Excellence.
  • Tejero J; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Rosengart MR; Acute Lung Injury Center of Excellence.
  • Mars WM; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Van Tyne D; Acute Lung Injury Center of Excellence.
  • Perlegas A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Brashears S; Acute Lung Injury Center of Excellence.
  • Kim-Shapiro DB; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Gladwin MT; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Bachman MA; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
  • Hod EA; Vascular Medicine Institute.
  • St Croix C; Department of Surgery.
  • Tyurina YY; Department of Pathology, and.
  • Kagan VE; Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Mallampalli RK; Department of Physics and The Translational Science Center, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Ray A; Department of Physics and The Translational Science Center, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Ray P; Department of Physics and The Translational Science Center, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Lee JS; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine.
J Clin Invest ; 131(1)2021 01 04.
Article in En | MEDLINE | ID: mdl-32941182
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phagocytosis / Gene Expression Regulation / Sepsis / Erythrocytes / STAT1 Transcription Factor / Heme / Immune Tolerance Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2021 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phagocytosis / Gene Expression Regulation / Sepsis / Erythrocytes / STAT1 Transcription Factor / Heme / Immune Tolerance Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2021 Document type: Article