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Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer.
Velasco, Ana; Tokat, Fatma; Bonde, Jesper; Trim, Nicola; Bauer, Elisabeth; Meeney, Adam; de Leng, Wendy; Chong, George; Dalstein, Véronique; Kis, Lorand L; Lorentzen, Jon A; Tomic, Snjezana; Thwaites, Keeley; Putzová, Martina; Birnbaum, Astrid; Qazi, Romena; Primmer, Vanessa; Dockhorn-Dworniczak, Barbara; Hernández-Losa, Javier; Soares, Fernando A; Gertler, Asaf A; Kalman, Michal; Wong, Chris; Carraro, Dirce M; Sousa, Ana C; Reis, Rui M; Fox, Stephen B; Fassan, Matteo; Brevet, Marie; Merkelbach-Bruse, Sabine; Colling, Richard; Soilleux, Elizabeth; Teo, Ryan Yee Wei; D'Haene, Nicky; Nolet, Serge; Ristimäki, Ari; Väisänen, Timo; Chapusot, Caroline; Soruri, Afsaneh; Unger, Tina; Wecgowiec, Johanna; Biscuola, Michele; Frattini, Milo; Long, Anna; Campregher, Paulo V; Matias-Guiu, Xavier.
Affiliation
  • Velasco A; Departments of Pathology and Molecular Genetics, Hospital U Arnau de Vilanova and Hospital U de Bellvitge, University of Lleida, IRBLLEIDA, IDIBELL, CIBERONC, Av. Alcalde Rovira Roure, 80 25198, Lleida, Spain. avelasco@gss.cat.
  • Tokat F; Department of Pathology, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
  • Bonde J; Molecular Pathology Laboratory, Department of Pathology, afs. 134, Hvidovre Hospital, Hvidovre, Denmark.
  • Trim N; Molecular Pathology Diagnostic Service, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Bauer E; Städtisches Klinikum Karlsruhe gGmbH, Institut für Pathologie, Karlsruhe, Germany.
  • Meeney A; Ophthalmic Pathology Laboratory Histopathology, Royal Hallamshire Hospital, Glossop Road, Sheffield, UK.
  • de Leng W; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Chong G; Molecular Pathology Centre, Jewish General Hospital-McGill University, Montreal, Quebec, Canada.
  • Dalstein V; Laboratoire de Biopathologie, Unité INSERM UMR-S 1250, CHU Reims, Reims, France.
  • Kis LL; Department of Clinical Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden.
  • Lorentzen JA; Molecular Pathology Unit, Department of Pathology, Oslo University Hospital, Oslo, Norway.
  • Tomic S; Department of Pathology, Forensic Medicine and Cytology, University Hospital Split, Split, Croatia.
  • Thwaites K; Histopathology Department, Barking, Havering and Redbridge University Hospitals NHS Trust, Queen's Hospital, Romford, UK.
  • Putzová M; Bioptická laborator s.r.o., Laboratory of Molecular Genetics, Plzen, Czech Republic.
  • Birnbaum A; ÚBLG FN Motol, Praha, Czech Republic.
  • Qazi R; LF UK, Plzen, Czech Republic.
  • Primmer V; Institute of Pathology, Dessau, Germany.
  • Dockhorn-Dworniczak B; Department of Pathology, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Johr Town, Lahore, Pakistan.
  • Hernández-Losa J; Pathologisch-Bakteriologisches Institut Kaiser-Franz-Josef-Spital, Vienna, Austria.
  • Soares FA; Zentrum für Pathologie Kempten-Allgäu (MVZ), Kempten, Germany.
  • Gertler AA; Department of Pathology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
  • Kalman M; Spanish Biomedical Research Network Centre in Oncology (CIBERONC), Madrid, Spain.
  • Wong C; Anatomia Patológica Rede D'Or, São Paulo, SP, Brazil.
  • Carraro DM; Department of Pathology, Hadassah Medical Center, Jerusalem, Israel.
  • Sousa AC; Department of Pathologic Anatomy, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovak Republic.
  • Reis RM; Martin's Biopsy Center Ltd., Martin, Slovak Republic.
  • Fox SB; Hong Kong Molecular Pathology Diagnostic Centre, Hong Kong Special Administrative Region of the People's Republic of China, Hong Kong, People's Republic of China.
  • Fassan M; Genomics and Molecular Biology Group, International Research Center/CIPE, A. C. Camargo Cancer Center, São Paulo, SP, Brazil.
  • Brevet M; GenoMed, Diagnósticos de Medicina Molecular, SA, Lisbon, Portugal.
  • Merkelbach-Bruse S; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil.
  • Colling R; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
  • Soilleux E; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.
  • Teo RYW; Pathology, Peter MacCallum Cancer Centre and University of Melbourne, Vic, Australia.
  • D'Haene N; Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
  • Nolet S; Department of Pathology, Hospices Civils de Lyon, Université Lyon 1, Bron, France & Cypath, Villeurbanne, France.
  • Ristimäki A; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
  • Väisänen T; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Chapusot C; Department of Pathology, University of Cambridge, Cambridge, UK.
  • Soruri A; Department of Pathology, Tan Tock Seng Hospital, Novena, Republic of Singapore.
  • Unger T; Department of Pathology, Erasme Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Wecgowiec J; Département de Pathologie et Biologie Cellulaire, Université de Montréal, Montreal, Québec, Canada.
  • Biscuola M; Department of Pathology, Research Programs Unit and HUSLAB, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Frattini M; Oulu University Hospital and Department of Pathology, Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.
  • Long A; Platform of Somatic Oncology of Burgundy, CHU, Dijon, France.
  • Campregher PV; Institut für Pathologie und Molekularpathologie, Pforzheim, Germany.
  • Matias-Guiu X; Institut für Pathologie, University of Leipzig, Leipzig, Germany.
Virchows Arch ; 478(5): 851-863, 2021 May.
Article in En | MEDLINE | ID: mdl-33170334
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Immunohistochemistry / Colorectal Neoplasms / Biomarkers, Tumor / Tissue Fixation / Paraffin Embedding / Microsatellite Instability / Mutation Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Virchows Arch Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Immunohistochemistry / Colorectal Neoplasms / Biomarkers, Tumor / Tissue Fixation / Paraffin Embedding / Microsatellite Instability / Mutation Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Virchows Arch Year: 2021 Document type: Article