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Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu, Xiao-Yi; Shi, Xiong-Jie; Hu, Ao; Wang, Ju-Qiong; Ding, Yi; Jiang, Wei; Sun, Ming; Zhao, Xiaolu; Luo, Jie; Qi, Wei; Song, Bao-Liang.
Affiliation
  • Lu XY; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Shi XJ; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Hu A; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Wang JQ; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Ding Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Jiang W; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Sun M; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Zhao X; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Luo J; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China.
  • Qi W; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Song BL; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, the Institute for Advanced Studies, Wuhan University, Wuhan, China. blsong@whu.edu.cn.
Nature ; 588(7838): 479-484, 2020 12.
Article in En | MEDLINE | ID: mdl-33177714
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Ubiquitin Thiolesterase / Eating / Mechanistic Target of Rapamycin Complex 1 / Hydroxymethylglutaryl CoA Reductases Limits: Animals / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Ubiquitin Thiolesterase / Eating / Mechanistic Target of Rapamycin Complex 1 / Hydroxymethylglutaryl CoA Reductases Limits: Animals / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article