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HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.
Ziegler, Maja C; Naidoo, Kewreshini; Chapel, Anais; Nkotwana, Sindiswa; Mann, Jaclyn; Mncube, Zenele; Ismael, Nasreen; Goulder, Philip; Ndung'u, Thumbi; Altfeld, Marcus; Thobakgale, Christina F.
Affiliation
  • Ziegler MC; Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Naidoo K; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Chapel A; Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Nkotwana S; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Mann J; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Mncube Z; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Ismael N; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Goulder P; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Ndung'u T; Department of Paediatrics, University of Oxford, Oxford, UK.
  • Altfeld M; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Thobakgale CF; Ragon Institute of MGH, MIT and Harvard University, Cambridge, Massachusetts, USA.
AIDS ; 35(1): 151-154, 2021 01 01.
Article in En | MEDLINE | ID: mdl-33273184

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Limits: Humans Language: En Journal: AIDS Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Limits: Humans Language: En Journal: AIDS Year: 2021 Document type: Article