Sodium ion channels as potential therapeutic targets for cancer metastasis.

Horne, Jesse; Mansur, Shomit; Bao, Yuping

Horne, Jesse; Mansur, Shomit; Bao, Yuping.

Affiliation

Horne J; Department of Chemical and Biomolecular Engineering, The University of Illinois at Urbana-Champaign, 114 Roger Adams Laboratory, MC 712 600 South Mathews Avenue, Urbana, IL 61801, USA.
Mansur S; Chemical and Biological Engineering, Box 370203, The University of Alabama, Tuscaloosa, AL 35487, USA.
Bao Y; Chemical and Biological Engineering, Box 370203, The University of Alabama, Tuscaloosa, AL 35487, USA. Electronic address: ybao@eng.ua.edu.

Drug Discov Today ; 26(5): 1136-1147, 2021 05.

Article in En | MEDLINE | ID: mdl-33545383

ABSTRACT

ABSTRACT

Is it possible to develop drugs for the treatment of a specific type of metastatic cancer by targeting sodium ion channels?

Subject(s)

Molecular Targeted Therapy; Neoplasms/pathology; Voltage-Gated Sodium Channels/metabolism; Animals; Antineoplastic Agents/pharmacology; Binding Sites; Drug Design; Drug Development/methods; Humans; Neoplasm Metastasis; Neoplasms/therapy; Voltage-Gated Sodium Channels/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Targeted Therapy / Voltage-Gated Sodium Channels / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Drug Discov Today Year: 2021 Document type: Article

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