ADAMTS5 is required for normal trabeculated bone development in the mandibular condyle.

Rogers-DeCotes, A W; Porto, S C; Dupuis, L E; Kern, C B

Rogers-DeCotes, A W; Porto, S C; Dupuis, L E; Kern, C B.

Affiliation

Rogers-DeCotes AW; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29525, USA.
Porto SC; Department of Health and Human Performance, College of Charleston, Charleston, SC, 29424, USA.
Dupuis LE; Medical University of South Carolina, Division of Cardiothoracic Surgery, Charleston, SC, 29525, USA.
Kern CB; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29525, USA. Electronic address: kernc@musc.edu.

Osteoarthritis Cartilage ; 29(4): 547-557, 2021 04.

Article in En | MEDLINE | ID: mdl-33561540

Subject(s)

ADAMTS5 Protein/genetics; Cancellous Bone/growth & development; Mandibular Condyle/growth & development; ADAMTS5 Protein/physiology; Animals; Cancellous Bone/diagnostic imaging; Cancellous Bone/metabolism; Chondrocytes/metabolism; Mandibular Condyle/diagnostic imaging; Mandibular Condyle/metabolism; Matrix Metalloproteinase 13/metabolism; Mesenchymal Stem Cells/metabolism; Mice; Mice, Knockout; Osteoblasts/metabolism; Osteocalcin/metabolism; Versicans/metabolism; X-Ray Microtomography; Zinc Finger Protein GLI1/metabolism

Key words

ADAMTS; Bone; Extracellular matrix; Mandibular condyle; Temporomandibular joint (TMJ)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancellous Bone / ADAMTS5 Protein / Mandibular Condyle Limits: Animals Language: En Journal: Osteoarthritis Cartilage Year: 2021 Document type: Article

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