Increased worsening of amyotrophic lateral sclerosis patients during Covid-19-related lockdown in France.
Amyotroph Lateral Scler Frontotemporal Degener
; 22(7-8): 505-507, 2021 11.
Article
in En
| MEDLINE
| ID: mdl-33576710
ABSTRACT
Covid-19-related lockdown (LD) in France precluded in-person follow-up in referral ALS centers. ALS patients' evolution and worsening before and during LD were studied to analyze its impact. A total of 84 patients were identified. The monthly rate of ALSFRS-R decline during LD was 1.06 ± 1.42 and was significantly increased compared to the pre-LD period, 0.58 ± 0.73, corresponding to an 83% increase (p = 0.007). Weight loss was unchanged between pre-LD and LD, gender and site of onset did not influence the rates of change of ALSFRS-R score. Several factors may be implicated in this increased severity of ALS during LD, such as psychological consequences of LD, interruptions of physiotherapy and speech therapy, or in-patient visits both to the tertiary center and the GP. Physicians and health authorities should be aware of that, in order to prevent the consequences of future sanitary restrictions.
Key words
Full text:
1
Collection:
01-internacional
Health context:
2_ODS3
/
4_TD
Database:
MEDLINE
Main subject:
COVID-19
/
Amyotrophic Lateral Sclerosis
Type of study:
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Amyotroph Lateral Scler Frontotemporal Degener
Year:
2021
Document type:
Article