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Ribavirin inhibits colorectal cancer growth by downregulating PRMT5 expression and H3R8me2s and H4R3me2s accumulation.
Ge, Suyin; Zhang, Qingqing; Chen, Yonglin; Tian, Yizhen; Yang, Ruiying; Chen, Xu; Li, Fang; Zhang, Baolai.
Affiliation
  • Ge S; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: gesy17@lzu.edu.cn.
  • Zhang Q; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: qqzhang18@lzu.edu.cn.
  • Chen Y; Department of Pathology, First Hospital, Lanzhou University, Lanzhou 730000, People's Republic of China.
  • Tian Y; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: tianyzh18@lzu.edu.cn.
  • Yang R; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: yangry20@lzu.edu.cn.
  • Chen X; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: chenxu15@lzu.edu.cn.
  • Li F; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: fli2019@lzu.edu.cn.
  • Zhang B; Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, People's Republic of China. Electronic address: zhangbl@lzu.edu.cn.
Toxicol Appl Pharmacol ; 415: 115450, 2021 03 15.
Article in En | MEDLINE | ID: mdl-33577917
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Ribavirin / Histones / Colorectal Neoplasms / DNA Methylation / Eukaryotic Initiation Factor-4E / Cell Proliferation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Ribavirin / Histones / Colorectal Neoplasms / DNA Methylation / Eukaryotic Initiation Factor-4E / Cell Proliferation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article