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Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells.
Wanjalla, Celestine N; McDonnell, Wyatt J; Ram, Ramesh; Chopra, Abha; Gangula, Rama; Leary, Shay; Mashayekhi, Mona; Simmons, Joshua D; Warren, Christian M; Bailin, Samuel; Gabriel, Curtis L; Guo, Liang; Furch, Briana D; Lima, Morgan C; Woodward, Beverly O; Hannah, LaToya; Pilkinton, Mark A; Fuller, Daniela T; Kawai, Kenji; Virmani, Renu; Finn, Aloke V; Hasty, Alyssa H; Mallal, Simon A; Kalams, Spyros A; Koethe, John R.
Affiliation
  • Wanjalla CN; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • McDonnell WJ; Center for Translational Immunology and Infectious Disease, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ram R; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Chopra A; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Gangula R; Center for Translational Immunology and Infectious Disease, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Leary S; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Mashayekhi M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, USA.
  • Simmons JD; 10x Genomics, Pleasanton, CA, USA.
  • Warren CM; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia.
  • Bailin S; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia.
  • Gabriel CL; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Guo L; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Furch BD; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia.
  • Lima MC; Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Woodward BO; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Hannah L; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Pilkinton MA; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Fuller DT; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kawai K; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Virmani R; Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University, Nashville, TN, USA.
  • Finn AV; CVPath Institute, Gaithersburg, MD, USA.
  • Hasty AH; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Mallal SA; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kalams SA; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Koethe JR; Tennessee Center for AIDS Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Cell Rep Med ; 2(2): 100205, 2021 02 16.
Article in En | MEDLINE | ID: mdl-33665640
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / HIV Infections / Adipose Tissue / Single-Cell Analysis Limits: Humans Language: En Journal: Cell Rep Med Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / HIV Infections / Adipose Tissue / Single-Cell Analysis Limits: Humans Language: En Journal: Cell Rep Med Year: 2021 Document type: Article