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Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.
Salcedo, Claudia; Wagner, Antonie; Andersen, Jens V; Vinten, Kasper Tore; Waagepetersen, Helle S; Schousboe, Arne; Freude, Kristine K; Aldana, Blanca I.
Affiliation
  • Salcedo C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Wagner A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Andersen JV; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Vinten KT; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Waagepetersen HS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Schousboe A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
  • Freude KK; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870, Frederiksberg, Denmark.
  • Aldana BI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark. blanca.aldana@sund.ku.dk.
Neurochem Res ; 46(10): 2676-2686, 2021 Oct.
Article in En | MEDLINE | ID: mdl-33710537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / GABA Plasma Membrane Transport Proteins / Induced Pluripotent Stem Cells / Alzheimer Disease / Gamma-Aminobutyric Acid Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Neurochem Res Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / GABA Plasma Membrane Transport Proteins / Induced Pluripotent Stem Cells / Alzheimer Disease / Gamma-Aminobutyric Acid Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Neurochem Res Year: 2021 Document type: Article