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Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis.
Takeuchi, Suguru; Tsuchiya, Atsunori; Iwasawa, Takahiro; Nojiri, Shunsuke; Watanabe, Takayuki; Ogawa, Masahiro; Yoshida, Tomoaki; Fujiki, Katsunori; Koui, Yuta; Kido, Taketomo; Yoshioka, Yusuke; Fujita, Mayu; Kikuta, Junichi; Itoh, Tohru; Takamura, Masaaki; Shirahige, Katsuhiko; Ishii, Masaru; Ochiya, Takahiro; Miyajima, Atsushi; Terai, Shuji.
Affiliation
  • Takeuchi S; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Tsuchiya A; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. atsunori@med.niigata-u.ac.jp.
  • Iwasawa T; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Nojiri S; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Watanabe T; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Ogawa M; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Yoshida T; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Fujiki K; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1, Yayoi-Cho, Bunkyo-ku, Tokyo, 113-0032, Japan.
  • Koui Y; Laboratory of Stem Cell Therapy, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan.
  • Kido T; Laboratory of Stem Cell Therapy, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan.
  • Yoshioka Y; Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, 6-7-1, Nishi-Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Fujita M; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
  • Kikuta J; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
  • Itoh T; Laboratory of Stem Cell Therapy, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan.
  • Takamura M; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
  • Shirahige K; Laboratory of Genome Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1, Yayoi-Cho, Bunkyo-ku, Tokyo, 113-0032, Japan.
  • Ishii M; Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
  • Ochiya T; Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, 6-7-1, Nishi-Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Miyajima A; Laboratory of Stem Cell Therapy, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan.
  • Terai S; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. terais@med.niigata-u.ac.jp.
NPJ Regen Med ; 6(1): 19, 2021 Mar 30.
Article in En | MEDLINE | ID: mdl-33785758
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: NPJ Regen Med Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: NPJ Regen Med Year: 2021 Document type: Article