MiR-137 promotes cell growth and inhibits extracellular matrix protein expression in H<sub>2</sub>O<sub>2</sub>-induced human trabecular meshwork cells by targeting Src.

Wang, Liang; Tian, Ying; Cao, Yan; Ma, Qiang; Zhao, Shuai

MiR-137 promotes cell growth and inhibits extracellular matrix protein expression in H₂O₂-induced human trabecular meshwork cells by targeting Src.

Wang, Liang; Tian, Ying; Cao, Yan; Ma, Qiang; Zhao, Shuai.

Affiliation

Wang L; Department of Ophthalmology, Xi'an NO.1 Hospital, Xi'an, 710002, China.
Tian Y; Department of Ophthalmology, Xi'an NO.1 Hospital, Xi'an, 710002, China.
Cao Y; Department of Ophthalmology, Xi'an NO.1 Hospital, Xi'an, 710002, China.
Ma Q; Department of Ophthalmology, Xi'an NO.1 Hospital, Xi'an, 710002, China.
Zhao S; Department of Ophthalmology, Xi'an NO.1 Hospital, Xi'an, 710002, China. Electronic address: hangsomezhao@163.com.

Neurosci Lett ; 755: 135902, 2021 06 11.

Article in En | MEDLINE | ID: mdl-33865939

Subject(s)

Cell Proliferation/physiology; Extracellular Matrix Proteins/biosynthesis; Hydrogen Peroxide/toxicity; MicroRNAs/biosynthesis; Proto-Oncogene Proteins pp60(c-src)/metabolism; Trabecular Meshwork/metabolism; Cell Proliferation/drug effects; Cell Survival/drug effects; Cell Survival/physiology; Cells, Cultured; Extracellular Matrix Proteins/antagonists & inhibitors; Extracellular Matrix Proteins/genetics; Gene Expression; Humans; MicroRNAs/genetics; Oxidative Stress/drug effects; Oxidative Stress/physiology; Proto-Oncogene Proteins pp60(c-src)/antagonists & inhibitors; Proto-Oncogene Proteins pp60(c-src)/genetics; Trabecular Meshwork/drug effects

Key words

Extracellular matrix; Glaucoma; Oxidative stress; miR-137

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trabecular Meshwork / Extracellular Matrix Proteins / Proto-Oncogene Proteins pp60(c-src) / MicroRNAs / Cell Proliferation / Hydrogen Peroxide Limits: Humans Language: En Journal: Neurosci Lett Year: 2021 Document type: Article

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