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Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation.
Englert, Hanna; Rangaswamy, Chandini; Deppermann, Carsten; Sperhake, Jan-Peter; Krisp, Christoph; Schreier, Danny; Gordon, Emma; Konrath, Sandra; Haddad, Munif; Pula, Giordano; Mailer, Reiner K; Schlüter, Hartmut; Kluge, Stefan; Langer, Florian; Püschel, Klaus; Panousis, Kosta; Stavrou, Evi X; Maas, Coen; Renné, Thomas; Frye, Maike.
Affiliation
  • Englert H; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Rangaswamy C; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Deppermann C; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Sperhake JP; Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Krisp C; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schreier D; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Gordon E; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
  • Konrath S; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Haddad M; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Pula G; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Mailer RK; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schlüter H; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kluge S; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Langer F; II. Medical Clinic and Polyclinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Püschel K; Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Panousis K; CSL Limited, BIO21 Institute, Parkville, Victoria, Australia.
  • Stavrou EX; Department of Medicine, Hematology and Oncology Division, CWRU School of Medicine, Cleveland, Ohio, USA; Department of Medicine, Section of Hematology-Oncology, Louis Stokes Veterans Administration Medical Center, Cleveland, Ohio, USA.
  • Maas C; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, University, Utrecht, the Netherlands.
  • Renné T; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Frye M; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: m.frye@uke.de.
EBioMedicine ; 67: 103382, 2021 May.
Article in En | MEDLINE | ID: mdl-34000623
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Full text: 1 Collection: 01-internacional Health context: 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Factor XII / Extracellular Traps / COVID-19 Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: EBioMedicine Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 4_TD / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Factor XII / Extracellular Traps / COVID-19 Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: EBioMedicine Year: 2021 Document type: Article