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A country-specific FRAX model for Botswana.
Kebaetse, M; Nkhwa, S; Mogodi, M; Masunge, J; Gureja, Y P; Ramabu, M; Mmopelwa, T; Sharif, I; Orford, A; Harvey, N C; McCloskey, E V; Cauley, J A; Kanis, J A; Johansson, H.
Affiliation
  • Kebaetse M; Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Nkhwa S; Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Mogodi M; Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Masunge J; Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Gureja YP; Princess Marina Hospital, Gaborone, Botswana.
  • Ramabu M; Princess Marina Hospital, Gaborone, Botswana.
  • Mmopelwa T; Gaborone Private Hospital, Gaborone, Botswana.
  • Sharif I; Bokamoso Private Hospital, Gaborone, Botswana.
  • Orford A; Gaborone Private Hospital, Gaborone, Botswana.
  • Harvey NC; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
  • McCloskey EV; Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
  • Cauley JA; Mellanby Centre for Musculoskeletal Research, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
  • Kanis JA; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
  • Johansson H; Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK. w.j.pontefract@sheffield.ac.uk.
Arch Osteoporos ; 16(1): 90, 2021 06 07.
Article in En | MEDLINE | ID: mdl-34100118
ABSTRACT

INTRODUCTION:

Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment.

OBJECTIVE:

This paper describes the development and characteristics of a country-specific FRAX model for Botswana.

METHODS:

Age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA.

RESULTS:

The probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia.

CONCLUSION:

The creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Osteoporotic Fractures / Hip Fractures Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: Africa Language: En Journal: Arch Osteoporos Year: 2021 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Osteoporotic Fractures / Hip Fractures Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: Africa Language: En Journal: Arch Osteoporos Year: 2021 Document type: Article