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Distinct modulation of tracheal and laryngopharyngeal cough via superior laryngeal nerve in cat.
Simera, Michal; Veternik, Marcel; Martvon, Lukas; Kotmanova, Zuzana; Mostafavi, Soheil; Bosko, Ondrej; Kralikova, Olga; Poliacek, Ivan.
Affiliation
  • Simera M; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic. Electronic address: simera@jfmed.uniba.sk.
  • Veternik M; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Martvon L; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Kotmanova Z; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Mostafavi S; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Bosko O; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Kralikova O; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
  • Poliacek I; Institute of Medical Biophysics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Malá Hora 4, 036 01 Martin, Slovak Republic.
Respir Physiol Neurobiol ; 293: 103716, 2021 11.
Article in En | MEDLINE | ID: mdl-34119702
Unilateral and bilateral cooling and bilateral transsection of the superior laryngeal nerve (SLN) were employed to modulate mechanically induced tracheobronchial (TB) and laryngopharyngeal (LPh) cough in 12 anesthetized cats. There was little effect of SLN block or cut on TB. Bilateral SLN cooling reduced the number of LPh (<50 %, p < 0.05), amplitudes of diaphragm EMG activity (<55 %, p < 0.05), and cough expiratory efforts (<40 %, p < 0.01) during LPh. Effects after unilateral SLN cooling were less pronounced. Temporal analysis of LPh showed only shortening of diaphragm and abdominal muscles burst overlap in the inspiratory-expiratory transition after unilateral SLN cooling. Bilateral cooling reduced both expiratory phase and total cough cycle duration. There was no significant difference in the average effects of cooling left or right SLN on LPh or TB as well as no differences in contralateral and ipsilateral diaphragm and abdominal EMG amplitudes. Our results show that reduced afferent drive in the SLN markedly attenuates LPh with virtually no effect on TB.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharynx / Reflex / Trachea / Cough / Laryngeal Nerves / Larynx Limits: Animals Language: En Journal: Respir Physiol Neurobiol Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharynx / Reflex / Trachea / Cough / Laryngeal Nerves / Larynx Limits: Animals Language: En Journal: Respir Physiol Neurobiol Year: 2021 Document type: Article