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Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study.
Gevaert, Philippe; De Craemer, Jarno; De Ruyck, Natalie; Rottey, Sylvie; de Hoon, Jan; Hellings, Peter W; Volckaert, Bram; Lesneuck, Kristof; Orengo, Jamie M; Atanasio, Amanda; Kamal, Mohamed A; Abdallah, Hisham; Kamat, Vishal; Dingman, Robert; DeVeaux, Michelle; Ramesh, Divya; Perlee, Lorah; Wang, Claire Q; Weinreich, David M; Herman, Gary; Yancopoulos, George D; O'Brien, Meagan P.
Affiliation
  • Gevaert P; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium.
  • De Craemer J; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium.
  • De Ruyck N; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium.
  • Rottey S; Drug Research Unit Ghent, Ghent University Hospital, Ghent, Belgium.
  • de Hoon J; Center for Clinical Pharmacology, UZ Leuven, Leuven, Belgium.
  • Hellings PW; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium; Allergy and Clinical Immunology Research Group, KU Leuven, Leuven, Belgium; Academic Medical Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands.
  • Volckaert B; SGS Belgium Clinical Pharmacology Unit Antwerpen, Antwerp, Belgium.
  • Lesneuck K; SGS Belgium Clinical Pharmacology Unit Antwerpen, Antwerp, Belgium.
  • Orengo JM; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Atanasio A; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Kamal MA; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Abdallah H; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Kamat V; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Dingman R; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • DeVeaux M; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Ramesh D; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Perlee L; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Wang CQ; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Weinreich DM; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Herman G; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • Yancopoulos GD; Regeneron Pharmaceuticals, Inc, Tarrytown, NY.
  • O'Brien MP; Regeneron Pharmaceuticals, Inc, Tarrytown, NY. Electronic address: meagan.obrien@regeneron.com.
J Allergy Clin Immunol ; 149(1): 189-199, 2022 01.
Article in En | MEDLINE | ID: mdl-34126156
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Allergens / Rhinitis, Allergic, Seasonal / Antigens, Plant / Antibodies, Monoclonal Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2022 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Allergens / Rhinitis, Allergic, Seasonal / Antigens, Plant / Antibodies, Monoclonal Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2022 Document type: Article