Your browser doesn't support javascript.
loading
Autoimmune glomerulonephritis in a multiple sclerosis patient after cladribine treatment.
Schönfelder, Kristina; Schuh, Helene; Pfister, Frederick; Krämer, Julia; Eisenberger, Ute; Skuljec, Jelena; Hackert, Jana; Ruck, Tobias; Pfeuffer, Steffen; Fleischer, Michael; Gäckler, Anja; Hagenacker, Tim; Kribben, Andreas; Meuth, Sven G; Kleinschnitz, Christoph; Pul, Refik.
Affiliation
  • Schönfelder K; Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Schuh H; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Pfister F; Department of Nephropathology, University Medicine Erlangen, Erlangen, Germany.
  • Krämer J; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
  • Eisenberger U; Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Skuljec J; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Hackert J; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Ruck T; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
  • Pfeuffer S; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
  • Fleischer M; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Gäckler A; Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Hagenacker T; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Kribben A; Department of Nephrology, University Medicine Essen, Essen, Germany Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Meuth SG; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
  • Kleinschnitz C; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
  • Pul R; Department of Neurology, University Medicine Essen, Essen, Germany/Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
Mult Scler ; 27(12): 1960-1964, 2021 10.
Article in En | MEDLINE | ID: mdl-34165361
ABSTRACT

BACKGROUND:

Oral cladribine is an approved disease-modifying drug for the treatment of relapsing multiple sclerosis. In controlled clinical trials as well as in post marketing safety assessments, autoimmune conditions have not yet been reported as a specific side effect of cladribine. OBJECTIVE AND

RESULTS:

Here, we report a case of anti-glomerular basement membrane antibody-mediated glomerulonephritis that occurred shortly after the fourth cladribine treatment cycle.

CONCLUSION:

Neurologists should be attentive to the development of secondary autoimmunity in cladribine-treated patients.
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Sclerosis, Relapsing-Remitting / Glomerulonephritis / Multiple Sclerosis Limits: Humans Language: En Journal: Mult Scler Year: 2021 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Sclerosis, Relapsing-Remitting / Glomerulonephritis / Multiple Sclerosis Limits: Humans Language: En Journal: Mult Scler Year: 2021 Document type: Article