Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank.

Widen, Erik; Raben, Timothy G; Lello, Louis; Hsu, Stephen D H

Widen, Erik; Raben, Timothy G; Lello, Louis; Hsu, Stephen D H.

Affiliation

Widen E; Department of Physics and Astronomy, Michigan State University, 567 Wilson Rd, East Lansing, MI 48824, USA.
Raben TG; Department of Physics and Astronomy, Michigan State University, 567 Wilson Rd, East Lansing, MI 48824, USA.
Lello L; Department of Physics and Astronomy, Michigan State University, 567 Wilson Rd, East Lansing, MI 48824, USA.
Hsu SDH; Genomic Prediction, Inc., 675 US Highway One, North Brunswick, NJ 08902, USA.

Genes (Basel) ; 12(7)2021 06 29.

Article in En | MEDLINE | ID: mdl-34209487

Subject(s)

Atherosclerosis/epidemiology; Biomarkers/blood; Biomarkers/urine; Cardiovascular Diseases/epidemiology; Lipoprotein(a)/blood; Adult; Atherosclerosis/blood; Atherosclerosis/urine; Biological Specimen Banks; Calcium/blood; Calcium/urine; Cardiovascular Diseases/blood; Female; Heart Disease Risk Factors; Hemoglobins/genetics; Humans; Lipoproteins, HDL/blood; Lipoproteins, LDL/blood; Machine Learning; Male; Middle Aged; Multifactorial Inheritance/genetics; Risk Assessment; United Kingdom/epidemiology; United States/epidemiology

Key words

atherosclerotic cardiovascular disease; biomarkers; disease risk; machine learning; polygenic scores

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Cardiovascular Diseases / Lipoprotein(a) / Atherosclerosis Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: America do norte / Europa Language: En Journal: Genes (Basel) Year: 2021 Document type: Article

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