RANKL expression in chondrocytes and its promotion by lymphotoxin-&#945; in the course of cartilage destruction during rheumatoid arthritis.

Takeshita, Ayumu; Nishida, Keiichiro; Yoshida, Aki; Nasu, Yoshihisa; Nakahara, Ryuichi; Kaneda, Daisuke; Ohashi, Hideki; Ozaki, Toshifumi

RANKL expression in chondrocytes and its promotion by lymphotoxin-α in the course of cartilage destruction during rheumatoid arthritis.

Takeshita, Ayumu; Nishida, Keiichiro; Yoshida, Aki; Nasu, Yoshihisa; Nakahara, Ryuichi; Kaneda, Daisuke; Ohashi, Hideki; Ozaki, Toshifumi.

Affiliation

Takeshita A; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nishida K; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Yoshida A; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nasu Y; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nakahara R; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Kaneda D; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ohashi H; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ozaki T; Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

PLoS One ; 16(7): e0254268, 2021.

Article in En | MEDLINE | ID: mdl-34234380

Subject(s)

Arthritis, Rheumatoid/metabolism; Chondrocytes/metabolism; Lymphotoxin-alpha/metabolism; RANK Ligand/metabolism; Adult; Aged; Aged, 80 and over; Cartilage, Articular/metabolism; Cells, Cultured; Female; Humans; Leukocytes, Mononuclear/metabolism; Ligands; Male; Middle Aged; Osteoarthritis/metabolism; Osteoclasts/metabolism; Receptor Activator of Nuclear Factor-kappa B/metabolism; Synovial Fluid/metabolism; Synovial Membrane/metabolism; Vascular Endothelial Growth Factor A/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Lymphotoxin-alpha / Chondrocytes / RANK Ligand Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Year: 2021 Document type: Article

Fulltext

XML

PubMed Links

Search on Google