Should we still only rely on EDSS to evaluate disability in multiple sclerosis patients? A study of inter and intra rater reliability.
Mult Scler Relat Disord
; 54: 103144, 2021 Sep.
Article
in En
| MEDLINE
| ID: mdl-34274736
ABSTRACT
BACKGROUND:
Few studies assessed reliability and inter-rater variability of EDSS and functional parameters (FP) rating.OBJECTIVE:
To evaluate inter-rater variability and errors in EDSS and FP rating in junior (JN) and MS Neurologists (MSN).METHOD:
Patients with MS were examined by a JN and a MSN on the same day. Each assessor rated FP and EDSS, then used a smartphone app to get an automated calculation for each FP ("smartphone" FP, sFP) and for EDSS ("smartphone" EDSS, sEDSS) from the description of the neurological exam. Inter-rater variability was assessed comparing JN and MSN ratings for each method. Intra-rater variability was assessed comparing traditional and digital rating for a given assessor.RESULT:
103 patients were included. Perfect agreement between JN and MSN was met for 67% and 70% of patients regarding EDSS and sEDSS. Disagreement that could lead to a significant difference in terms of level of disability occurred in 17% for EDSS and 12% for sEDSS (p=0.07). Regarding intra-rater reliability, we found 38 rating discrepancies for JN and 14 for MSN (p=0.04).CONCLUSION:
We found a significant inter-rater variability as well as a substantial frequency of rating errors in JN. The use of less subjective, easier-to-rate scales should be encouraged.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Disabled Persons
/
Multiple Sclerosis
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Mult Scler Relat Disord
Year:
2021
Document type:
Article